Aurora B kinase is a protein too runs in the attachment of the mitotic spindle to the centromere. Chromosomal segregation through mitosis as perfectly as meiosis is regulated by kinases and phosphatases.
The Aurora kinases associate providing microtubules through chromosome movement and segregation. Aurora kinase B localizes to microtubules pretty well kinetochores, specifically to the professional microtubules identified K-fibers, and Aurora kinase A localizes to centrosomes . In cancerous cells, over-expression of such enzymes leads unequal distribution of genetic information, making aneuploid cells, a hallmark of cancer.
Aurora kinase B Synonyms:
Aik2, AIK2, AIM1, AIM-1, ARK2, ARK-2, AurB, aurkb-sv1, aurkb-sv2, Aurora/IPL1-related kinase 2, Aurora-and IPL1-like midbody-associated protein 1, Aurora kinase B, Aurora-related kinase 2, IPL1, Serine/threonine-protein kinase 12, Serine/threonine-protein kinase aurora-B, STK-1, STK12, STK5
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